产品货号：
Z15830
中文名称：
DcR1/TNFRSF10C抗体
英文名称：
Anti-DcR1/TNFRSF10C Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DcR1/TNFRSF10C Antibody |
| 指标别名 | LIT;DCR1;TRID;CD263;TRAILR3;TRAIL-R3;DCR1-TNFR;LIT;UNQ321/PRO366;Tumor necrosis factor receptor superfamily member 10C;Decoy TRAIL receptor without death domain;DcR1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | TNFRSF10C |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | DcR1 antibody was raised against a peptide corresponding to amino acids in a extracellular domain of human DcR1 precursor.The immunogen is located within amino acids 140 - 190 of DcR1. |
| 计算分子量 | 27kDa |
| 成分 | DcR1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | DcR1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors.TRAIL/Apo2L is a new member of the TNF family and induces apoptosis of a variety of tumor cell lines.DR4 and DR5 are the recently identified functional receptors for TRAIL.Two decoy receptors for TRAIL have been identified and designated DcR1/TRID/TRAIL-R3/LIT and DcR2/TRAIL-R4/TRUNDD.DcR1 has extracellular TRAIL-binding domain but lacks intracellular signaling domain.It is a glycophospholipid-anchored cell surface protein.DcR1 transcripts were expressed in many normal human tissues but not in most cancer cell lines.Overexpression of DcR1 did not induce apoptosis,but attenuated TRAIL-induced apoptosis. |
| Uniprot ID | O14798 |
| 基因名全称 | Tumor necrosis factor receptor superfamily,member 10c,decoy without an intracellular domain |
| 蛋白名全称 | Tumor necrosis factor receptor superfamily,member 10c,decoy without an intracellular domain |
| 推荐稀释比 | DcR1 antibody can be used for detection of DcR1 by Western blot 0.5μg/mL.An approximate 65kDa band can be detected.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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